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Health And Beauty Tips
3 Holiday Makeup Looks
Adverse food reactions
Allergic rhinitis
Anaphylactic shock adults
At the scene of an accident
Avoiding allergens
Babies failing to thrive
Back injuries
Children and young people
ColdMediDangerous Infants
Colds and flu
Disguise a Double Chin
Drinking Coffee Helps Fight Alzheimer's,
Drug allergy
Eye Allergies
Finding the time
Foods th8Lower Cholesterol
Grass-Fed Beef The Natural Alternative
Head Injury
Heart Attack
Help for Tired Eyes
Hepatitis C
How much exercise do I need
Injuries and treatment
Look Younger by Morning
Lung cancer cases
Maintaining  target weight
Makeup Tricks 4 Dark Skin
Match Makeup 2 Your Outfit
Moving on
Opening airway
Perfect Lipstick
Fixes CommonHair Problem
Recovery position
Risky Business for Teens
Sensible slimming
Sleep Disorders
Summer hay fever
Supporting someone with cancer
Tips to give up smoking
Venom allergies
What's the right activity 4me
Why get fit
More Tips










                                                      Health And Beauty



Drug allergy

About 15 per cent of the UK population report adverse reactions
to medication, but only five per cent are truly allergic reactions.
Adverse reactions usually involve the immune system. Of these
less than one per cent are fatal.

Reactions can be divided into three groups:

Those not related to the drug but coincidental and due to
factors other than the drug. For example, rashes or nausea
associated with the disease and not the medication.

Toxic effects: from taking an overdose; those due to known
side effects; and those due to interactions with other medication
taken at the same time.

Then there are allergic reactions and these adverse reactions
usually involve the immune system.

What are the causes?
These may be due to direct anaphylactic immune reactions such as seen
with penicillin, vaccines, blood transfusions, insulin and intravenous

Triggers include aspirin and anti-inflammatory drugs

Other medicines can trigger histamine release in the body by
non-immune mechanisms and for which no diagnostic blood tests
are available. Triggers include aspirin and anti-inflammatory drugs,
morphine and the opiates, local anaesthetics and some fluids given
intravenously during x-ray.

Drugs that cause allergic reactions:

antibiotics - penicillin, sulphonamides, chloramphenicol and

heart drugs - ACE inhibitors, quinidine, amiodarone, methyldopa

anaesthetic drugs - muscle relaxants, thiopentone, halothane

morphine derivatives - morphine, pethidine and codeine

aspirin-like drugs - diclofenac, ibuprofen, indomethacin

cancer chemotherapy drugs - cisplatin, cyclophosphamide,

antiseptics - chlorhexidine, iodine

vaccines such as tetanus toxoid and diphtheria vaccine

preservatives such as Parabens and Benzakonium chloride

anticonvulsants, antituberculosis medication, streptokinase,
insulin, enzymes and latex

What are the symptoms?
The reaction may progress to life threatening anaphylaxis.

Most reactions occur within one hour and involve measles-like
itchy rashes or urticaria. A severe form may even blister
(Stevens-Johnson Syndrome). The reaction may progress to life
threatening anaphylaxis. Delayed reactions can develop days after
exposure to the drug with generalised dermatitis and damage to
organs such as the kidneys, liver, lungs and blood cells.

What is the treatment?
Treatment involves immediate withdrawal of the implicated drug,
followed by antihistamine medication. In cases of anaphylaxis,
the prompt use of adrenaline and steroids is life saving.

A blood test will confirm if an allergic reaction has taken place.
Unfortunately only penicillin, amoxycillin, sulphonamide and
cephalosporin allergy can be reliably confirmed by RAST testing.
If any other drug is suspected then skin testing, followed by challenge
tests in a hospital will be needed. Patch tests on the skin can test
allergy to certain drugs such as neomycin and the paraben preservatives.

What can be done to prevent drug allergies?
If you are allergic to a member of family of drugs such as penicillin or
aspirin, then all other members of that family should be avoided unless
negative skin or challenge tests have been performed. And if you're
allergic to penicillin, use the Erythromycin family of antibiotics instead.
The same goes for anti-inflammatory medication such as ibuprofen -
only use paracetamol.

It is possible to have an allergic reaction to almost any drug - including
paracetamol - so only use medication if absolutely necessary or if it has
been specifically prescribed to you. Never use someone else's medication
unless you have taken medical advice and are sure it is safe to use.


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